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RESISTING UPTO 99.9% ANTIBIOTICS: INDIA’S SUPERBUG WAR BEGINS

Last month, a study highlighted that Indians are highly resistant to some of the newer antibiotics. And this resistance is only increasing

Kerala—the first Indian state to draft and execute an antimicrobial resistance (AMR) action plan—held a meeting to call other states to action

While Indian states are starting work on preventing AMR, drugs needed to treat resistant tuberculosis are running out of stock

As Indians are fed more antibiotics than they need and those who need them struggle to access them, will the central government act?

he Indian Council of Medical Research, in 2013, initiated the Antimicrobial Resistance Surveillance & Research Network (AMRSN) to enable compilation of data on six pathogenic groups on antimicrobial resistance from the country. The overarching aim of this network was to understand the extent and pattern of antimicrobial resistance (AMR) and use this evidence to guide strategies to control the spread of AMR. 

Combined resistance to third-generation cephalosporins and fluoroquinolones and increasing carbapenem resistance are worrisome, as it has an important bearing on the patients' outcome and thus needs to be addressed urgently. Data generated through this Network have been used to develop treatment guidelines, which will be supportive in harmonizing treatment practices across the tertiary level healthcare institutions in the country. While, the major benefit of having a surveillance system is the collection of real-time accurate data on AMR including the mechanisms of resistance, representativeness to community, sustaining the current effort and expanding the current activities to next levels of healthcare settings are the major challenges. The data emanating from the network besides providing evidence, expose several gaps and lacunae in the ecosystem and highlight opportunities for action by multiple stakeholders.

The efficacy of several antibiotics is threatened by the emergence of resistant microorganisms. Multiple interlinked factors including high burden of disease, poor public health infrastructure, lack of appropriate diagnostic support, poor infection control practices and the tendency of clinicians to continue empirical treatment practices, have amplified the crisis of AMR in India [2]. Unregulated over-the-counter availability of antibiotics and non-compliance to the recommended treatment duration have been recognized as key drivers for the emergence of resistance in India [3]

http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2019;volume=149;issue=2;spage=164;epage=179;aulast=Walia

https://the-ken.com/story/resisting-antibiotics-indias-superbug/

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Comment(s)

Antibiotic resistance, when germs (i.e., bacteria, fungi) develop the ability to defeat the drugs designed to kill them, is a top threat to the public’s health and a priority across the globe. In the U.S. alone, it causes more than 2 million infections and 23,000 deaths per year. Worldwide, antibiotic resistance threatens our progress in healthcare, food production, and ultimately life expectancy.

This is an unfortunate consequence of physicians' overuse of antibiotics and consumer ignorance

15-Jul-2019

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Replies

Hi feminist,
Thanks for your comments. The emerging drug resistance is a serious global threat and possesses a significant challenge to public health. India alone accounted for 24% of global MDR TB incidence and 27% of global TB incidence among HIV-negative individuals.


19-Jul-2019

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