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Resisting upto 99.9% antibiotics: India’s superbug war begins

Resisting Upto 99.9% Antibiotics: India’s Superbug War Begins




  • Posted On : 11-Jul-2019
Last month, a study highlighted that Indians are highly resistant to some of the newer antibiotics. And this resistance is only increasing Kerala—the first Indian state to draft and execute an antimicrobial resistance (AMR) action plan—held a meeting to call other states to action While Indian states are starting work on preventing AMR, drugs needed to treat resistant tuberculosis are running out of stock As Indians are fed more antibiotics than they need and those who need them struggle to access them, will the central government act? he Indian Council of Medical Research, in 2013, initiated the Antimicrobial Resistance Surveillance & Research Network (AMRSN) to enable compilation of data on six pathogenic groups on antimicrobial resistance from the country. The overarching aim of this network was to understand the extent and pattern of antimicrobial resistance (AMR) and use this evidence to guide strategies to control the spread of AMR. Combined resistance to third-generation cephalosporins and fluoroquinolones and increasing carbapenem resistance are worrisome, as it has an important bearing on the patients' outcome and thus needs to be addressed urgently. Data generated through this Network have been used to develop treatment guidelines, which will be supportive in harmonizing treatment practices across the tertiary level healthcare institutions in the country. While, the major benefit of having a surveillance system is the collection of real-time accurate data on AMR including the mechanisms of resistance, representativeness to community, sustaining the current effort and expanding the current activities to next levels of healthcare settings are the major challenges. The data emanating from the network besides providing evidence, expose several gaps and lacunae in the ecosystem and highlight opportunities for action by multiple stakeholders. The efficacy of several antibiotics is threatened by the emergence of resistant microorganisms. Multiple interlinked factors including high burden of disease, poor public health infrastructure, lack of appropriate diagnostic support, poor infection control practices and the tendency of clinicians to continue empirical treatment practices, have amplified the crisis of AMR in India [2]. Unregulated over-the-counter availability of antibiotics and non-compliance to the recommended treatment duration have been recognized as key drivers for the emergence of resistance in India [3];year=2019;volume=149;issue=2;spage=164;epage=179;aulast=Walia


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